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In molecular biology, the protein domain UBA is short for ubiquitin-associated domains. Ubiquitin is a signal added to an incorrectly folded protein, which allows it to be degraded by the proteasome, and the amino acid constituents can be recycled. ==Function== This family of proteins is involved in a variety of additional cell processes, such as nucleotide excision repair (NER), spindle pole body duplication, and cell growth. Protein degradation via the ubiquitin proteasome system (UPS) allows the cell to selectively negatively regulate intracellular proteins. Protein degradation helps to maintain protein quality control, signalling, and cell cycle progression. UBA has be proposed to limit ubiquitin chain elongation and to target polyubiquitinated proteins to the 26S proteasome for degradation.〔They have been identified in modular proteins involved in protein trafficking, DNA repair, proteasomal degradation, and cell cycle regulation. UBA bind to ubiquitin and aids all the cellular processes involved with ubiquitin; this includes: *Antigen processing *Apoptosis *Biogenesis of organelles *Cell cycle and division *DNA transcription and DNA repair *Differentiation and development *Immune response and inflammation *Neural and muscular degeneration *Morphogenesis of neural networks *Modulation of cell surface receptors, ion channels and the secretory pathway *Response to stress and extracellular modulators *Ribosome biogenesis *Viral infection 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「UBA protein domain」の詳細全文を読む スポンサード リンク
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